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5-Hydroxydecanoic acid

CAS No. 624-00-0

5-Hydroxydecanoic acid( —— )

Catalog No. M34484 CAS No. 624-00-0

5-Hydroxydecanoate sodium is a selective ATP-sensitive K+ (KATP) channel blocker (IC50 of ~30 μM). 5-Hydroxydecanoate sodium is a substrate for mitochondrial outer membrane acyl-CoA synthetase and has antioxidant activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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25MG 54 In Stock
50MG 90 In Stock
100MG 128 In Stock
200MG 191 In Stock
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Biological Information

  • Product Name
    5-Hydroxydecanoic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    5-Hydroxydecanoate sodium is a selective ATP-sensitive K+ (KATP) channel blocker (IC50 of ~30 μM). 5-Hydroxydecanoate sodium is a substrate for mitochondrial outer membrane acyl-CoA synthetase and has antioxidant activity.
  • Description
    5-Hydroxydecanoic acid (5-HD） is a KATP channel antagonist，which has the effect of blocking the K KATP channel only during ischaemia by competing with the ATP binding site and does not affect pancreatic KATP channels.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Endocrinology/Hormones
  • Target
    ATPase
  • Recptor
    ATPase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    624-00-0
  • Formula Weight
    188.26
  • Molecular Formula
    C10H20O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(O)CCCC(O)CCCCC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. J A Auchampach, et al. Blockade of ischaemic preconditioning in dogs by the novel ATP dependent potassium channel antagonist sodium 5-hydroxydecanoate. Cardiovasc Res. 1992 Nov;26(11):1054-62.?
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